BDBM50014416 CHEMBL3261153

SMILES OC[C@@H](O)CNC(=O)c1nc(Cl)ncc1Nc1ccc(I)cc1F

InChI Key InChIKey=CDGIQRUGHAEJFI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014416   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014416(CHEMBL3261153)
Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014416(CHEMBL3261153)
Affinity DataIC50: 44nMAssay Description:Inhibition of MEK1 in human COLO205 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed