BDBM50014451 (+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-cyclohexyl ester::(-)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-cyclohexyl ester::CHEMBL105298

SMILES CC(C)C1CCC(C)CC1OC(=O)Cc1ccncc1

InChI Key InChIKey=LMEZSWOUANEVQS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50014451   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Concentration required to inhibit 50% activity of rat testicular Cytochrome P450 steroid 17alpha-hydroxylase/17,20 lyase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  5.10E+3nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50014451((+)-Pyridin-4-yl-acetic acid 2-isopropyl-5-methyl-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Concentration required to inhibit 50% activity of rat testicular Cytochrome P450 steroid 17alpha-hydroxylase/17,20 lyase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed