BDBM50014491 2-{4-[(2-Difluoromethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL102506

SMILES C#CCN(Cc1ccc2nc(C(F)F)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1

InChI Key InChIKey=DQLSOZZEWXTSGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014491   

TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014491BDBM50014491(CHEMBL102506 | 2-{4-[(2-Difluoromethyl-4-oxo-3,4-d...)
Affinity DataIC50: 580nMAssay Description:Binding affinity against Thymidylate synthase was measured in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed