BDBM50014668 6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322656

SMILES Cc1ccc(C2CC3CCC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50014668   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50014668(CHEMBL322656 | 6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl...)
Affinity DataIC50: 1.26E+3nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50014668(CHEMBL322656 | 6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50014668(CHEMBL322656 | 6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl...)
Affinity DataIC50: 3.16E+3nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50014668(CHEMBL322656 | 6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl...)
Affinity DataIC50: 3.20E+3nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed