BDBM50015010 CHEMBL3262091

SMILES CC[C@@](O)(c1ccccc1)[C@H]1C[C@@]23CC[C@]1(OC)[C@@H]1Oc4c(O)ccc5c4[C@@]12CCN(CC1CC1)[C@@H]3C5

InChI Key InChIKey=GFFDOSHSNIMJQO-UHFFFAOYSA-N

Data  4 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50015010   

TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015010BDBM50015010(CHEMBL3262091)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]-U69,593 from human kappa opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015010BDBM50015010(CHEMBL3262091)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015010BDBM50015010(CHEMBL3262091)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015010BDBM50015010(CHEMBL3262091)
Affinity DataEC50:  8.90nMAssay Description:Agonist activity at human delta opioid receptor transfected in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by beta-plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015010BDBM50015010(CHEMBL3262091)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human mu opioid receptor transfected in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by beta-plate l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015010BDBM50015010(CHEMBL3262091)
Affinity DataEC50:  249nMAssay Description:Agonist activity at human kappa opioid receptor transfected in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by beta-plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
University of Bath

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015010BDBM50015010(CHEMBL3262091)
Affinity DataKi:  396nMAssay Description:Displacement of [3H]-N/OFQ from human nociceptin opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed