BDBM50015296 CHEMBL3263076::US9120798, 13
SMILES Cc1cc(-c2nnc(Nc3ccccc3N3CC4(CCN(CC(C)(C)C)CC4)c4c3c(O)ccc4Cl)s2)n(C)n1
InChI Key InChIKey=QHBAYXBBRZABLL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50015296
Affinity DataKi: 6.60nMAssay Description:Displacement of [33P]2-MeS-ADP from human cloned P2Y1 receptor expressed in HEK293 cells by SPA analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of P2Y1 receptor in human washed platelets assessed as decrease in 2-methylthio-ADP-induced calcium signal transduction pathway activation...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:A membrane binding assay was used to identify inhibitors of [33P] 2MeS- ADP binding to cloned human P2Y1 receptors. The cDNA clone for human P2Yi was...More data for this Ligand-Target Pair