BDBM50015659 CHEMBL3260573::USRE47141, Example 42

SMILES COc1ccccc1NCc1nc(-c2ccc3ncnn3c2)c(-c2cccc(C)n2)[nH]1

InChI Key InChIKey=ZBIRZMVPLGYXSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015659   

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015659BDBM50015659(CHEMBL3260573 | USRE47141, Example 42)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015659BDBM50015659(CHEMBL3260573 | USRE47141, Example 42)
Affinity DataIC50: 14.4nMAssay Description:ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015659BDBM50015659(CHEMBL3260573 | USRE47141, Example 42)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as substrate by radioisotopic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed