BDBM50015676 CHEMBL3260589::USRE47141, Example 55

SMILES CSc1cccc(NCc2nc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)[nH]2)c1

InChI Key InChIKey=BRFBWBYMLHDXOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015676   

TargetTGF-beta receptor type-1(Human)
Ewha University—Industry Collaboration Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50015676BDBM50015676(CHEMBL3260589 | USRE47141, Example 55)
Affinity DataIC50: 6.70nMAssay Description:ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Ewha University—Industry Collaboration Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50015676BDBM50015676(CHEMBL3260589 | USRE47141, Example 55)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha University—Industry Collaboration Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50015676BDBM50015676(CHEMBL3260589 | USRE47141, Example 55)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as substrate by radioisotopic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed