BDBM50016033 CHEMBL3085574::{1-[1-{1-[2-(1-Benzylcarbamoyl-3-methyl-butylcarbamoyl)-1-hydroxy-ethyl]-3-methyl-butylcarbamoyl}-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)NCc1ccccc1
InChI Key InChIKey=AJSUGOHRKILWCK-ZZTWKDBPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50016033
Affinity DataKi: 18nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using a synthetic tetradecapeptide renin substrate at 10e-9 M concentrationMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibition of purified human kidney renin, radioimmunoassay using the natural substrate partially pure angiotensinogen at 10e-9 M concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of porcine kidney reninMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibitory activity against human reninMore data for this Ligand-Target Pair