BDBM50016673 CHEMBL52896::N-Hydroxy-N-methyl-2-[4-(quinolin-2-ylmethoxy)-phenyl]-acetamide

SMILES CN(O)C(=O)Cc1ccc(OCc2ccc3ccccc3n2)cc1

InChI Key InChIKey=HIMOIVVELGFEPX-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50016673   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataKi:  800nMAssay Description:In vitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataKi:  1.00E+3nMAssay Description:Activity to bind against [3H]LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016673(CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed