BDBM50017207 CHEMBL3287722::US10099993, Compound 71

SMILES CCCC(=O)c1ccc(OCCCCOc2ccc(cc2C)C(O)=O)c(C)c1O

InChI Key InChIKey=AAIOMRHKGUVZIS-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017207   

TargetMetabotropic glutamate receptor 3(Rat)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails US Patent


TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50:  104nMpH: 7.3 T: 25°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50:  104nMAssay Description:Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed