BDBM50018668 CHEMBL3291011

SMILES OP(O)(=O)C(NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)P(O)(O)=O

InChI Key InChIKey=GGXPSOYEDIWMFG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50018668   

TargetCarbonic anhydrase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 pretreated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  2.66E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 pretreated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 pretreated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  37nMAssay Description:Inhibition of human recombinant MMP-2 pretreated for 30 mins measured 2 to 4 hrs after Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP-14 (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 12(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  476nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 pretreated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  37nMAssay Description:Inhibition of MMP-2 (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeutrophil collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  320nMAssay Description:Inhibition of MMP-8 (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP-9 (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 9(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50018668(CHEMBL3291011)
Affinity DataIC50:  6.13E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 pretreated for 15 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed