BDBM50018734 1,4,5,7,8,9,10,10a-Octahydro-pyrazolo[3,4-a]quinolizine::CHEMBL156283

SMILES C1CCN2CCc3cn[nH]c3C2C1

InChI Key InChIKey=FIWQPBGSTABWLI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018734   

TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(1,4,5,7,8,9,10,10a-Octahydro-pyrazolo[3,4-a]quinol...)
Affinity DataKi:  9.55E+3nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(1,4,5,7,8,9,10,10a-Octahydro-pyrazolo[3,4-a]quinol...)
Affinity DataKi:  9.60E+3nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(1,4,5,7,8,9,10,10a-Octahydro-pyrazolo[3,4-a]quinol...)
Affinity DataKi:  2.40E+4nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]-clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018734(1,4,5,7,8,9,10,10a-Octahydro-pyrazolo[3,4-a]quinol...)
Affinity DataKi:  2.40E+4nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed