BDBM50018895 CHEMBL3287088

SMILES COc1cc(CC(O)=O)ccc1Oc1ccc2[nH]c(cc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl)C#N

InChI Key InChIKey=VTHNJTYEXNUZAR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018895   

TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50018895(CHEMBL3287088)
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK293 cells in buffer solution with 0.5% bovine serum albumin by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50018895(CHEMBL3287088)
Affinity DataIC50: 82nMAssay Description:Displacement of [3H]-PGD2 from human DP receptor expressed in HEK293 cells in buffer solution with 0.5% bovine serum albumin by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50018895(CHEMBL3287088)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]-PGD2 from human DP receptor expressed in HEK293 cells in presence of 50% human plasma by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50018895(CHEMBL3287088)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK293 cells in presence of 50% human plasma by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed