BDBM50019686 2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (4-pyrimidin-5-yl-butyl)-amide::CHEMBL294706

SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCCCc1cncnc1

InChI Key InChIKey=RUAOGLCGDIBHJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019686   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50019686(CHEMBL294706 | 2-Isopropyl-11-oxo-11H-pyrido[2,1-b...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human platelet thromboxane synthase (TXA2) was determined in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019686(CHEMBL294706 | 2-Isopropyl-11-oxo-11H-pyrido[2,1-b...)
Affinity DataIC50: 450nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed