BDBM50020590 CHEMBL2392187

SMILES [#6]-[#8]-c1cc(\[#6]=[#6]\[#6](=O)-[#6]-[#6](=O)\[#6]=[#6]\c2cc(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c(-[#8]-[#6])c2)cc(-[#6]\[#6]=[#6](\[#6])-[#6])c1-[#8]

InChI Key InChIKey=IOFXSNNIVTWGOH-UTLPMFLDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020590   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50020590(CHEMBL2392187)
Affinity DataIC50:  700nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli Bl21 (DE3) using arachidonic acid as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50020590(CHEMBL2392187)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of STAT3 transcriptional activity in human HaCaT cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed