BDBM50020676 CHEBI:41846::CHEMBL566812

SMILES Cc1cn([C@H]2CC[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)[nH]c1=O

InChI Key InChIKey=URGJWIFLBWJRMF-JGVFFNPUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020676   

TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020676(CHEBI:41846 | CHEMBL566812)
Affinity DataIC50:  3.08E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50020676(CHEBI:41846 | CHEMBL566812)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human DNA polymerase beta using 5' end radiolabeled 24nt DNA/48nt DNA as primer/template after 5 mins by PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020676(CHEBI:41846 | CHEMBL566812)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed