BDBM50021213 1-(3,4-Dichloro-phenyl)-3-methylamino-indan-5-ol::CHEMBL301514

SMILES CNC1CC(c2ccc(O)cc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=QAOIAICAGBDCEV-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50021213   

LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataKi:  11nMAssay Description:Binding affinity for DA transporter using [125I]RTI-55 in frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021213(CHEMBL301514 | 1-(3,4-Dichloro-phenyl)-3-methylami...)
Affinity DataKi:  24nMAssay Description:Reuptake inhibitory activity against NE transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed