BDBM50021882 CHEMBL3298831

SMILES O[C@@H](CNCCc1ccc(Nc2ccc(OCCN3CCOCC3)cc2)cc1)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=GPANSMBREMKPKY-UHFFFAOYSA-N

Data  1 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50021882   

TargetBeta-2 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50021882(CHEMBL3298831)
Affinity DataEC50:  0.316nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50021882(CHEMBL3298831)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human beta2 adrenergic receptor in human BEAS-2B cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50021882(CHEMBL3298831)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human beta1 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50021882(CHEMBL3298831)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]dihydroalprenolol from human beta2 adrenergic receptor expressing cell membrane by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50021882(CHEMBL3298831)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed