BDBM50022387 2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido[3,2-d]pyrimidin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid::CHEMBL36639

SMILES Nc1nc2c(c(=O)[nH]1)NC(CNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)CC2

InChI Key InChIKey=HLQVKHILGYCUSU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022387   

TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Sri International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022387BDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
Sri International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022387BDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022387BDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022387BDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed