BDBM50022649 CHEMBL76458::N-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethyl]-2-(3,3-dimethyl-ureido)-3-phenyl-propionamide

SMILES CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)N(C)C

InChI Key InChIKey=BUTLRPLOHRQFSC-MYHRABSESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022649   

TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022649(CHEMBL76458 | N-[1-(1-Cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.5nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022649(CHEMBL76458 | N-[1-(1-Cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  3.30nMpH: 7.4Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed