BDBM50022759 CHEMBL3298273
SMILES Fc1cccc(COc2ccc3C(=O)NCCc3n2)c1
InChI Key InChIKey=FMUAFDSEYCJYKD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50022759
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataEC50: 370nMAssay Description:Positive allosteric modulator activity at human mGlu5 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu1 receptor expressed in HEK293 cells assessed as glutamate-induced calcium mobilization treated 140...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu2 receptor expressed in HEK293 cells assessed as glutamate-induced GIRK channel-mediated thallium f...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor expressed in HEK293 cells assessed as glutamate-induced GIRK channel-mediated thallium f...More data for this Ligand-Target Pair
Affinity DataEC50: 224nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu7 receptor expressed in HEK293 cells assessed as L-AP4-induced GIRK channel-mediated thallium flux ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu8 receptor expressed in HEK293 cells assessed as glutamate-induced GIRK channel-mediated thallium f...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu6 receptor expressed in HEK293 cells assessed as glutamate-induced GIRK channel-mediated thallium f...More data for this Ligand-Target Pair