BDBM50023323 2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid (4-pyrimidin-5-yl-butyl)-amide::CHEMBL143914

SMILES Cc1cc2nc3ccc(cn3c(=O)c2cc1C)C(=O)NCCCCc1cncnc1

InChI Key InChIKey=GAXHRSHQGJGGRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023323   

TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023323(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8...)
Affinity DataIC50: 100nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed