BDBM50024102 ((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-acetic acid::(2-MERCAPTOMETHYL-3-PHENYL-PROPIONYL)-GLYCINE::(S) (2-Mercaptomethyl-3-phenyl-propionylamino)-acetic acid::2-[1-(2-Carboxy-2-hydroxy-ethylcarbamoyl)-2-phenyl-ethylamino]-4-phenyl-butyric acid(Thiorphan)::CHEMBL298827
SMILES OC(=O)CNC(=O)[C@@H](CS)Cc1ccccc1
InChI Key InChIKey=LJJKNPQAGWVLDQ-SNVBAGLBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50024102
Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Tested for binding affinity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to neutral endopeptidase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Compound was evaluated for inhibition of recombinant human neprilysin(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of recombinant human Neprilysin using Suc-Ala-Ala-Phe-AMC as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity to angiotensin-converting enzyme (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Tested for binding against ThermolysinMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human Aminopeptidase N using L-Ala-beta-NA as substrate preincubated for 30 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human ACE using MCA-RPPGFSAFK-Dnp-OH as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human NEP using MCA-RPPGFSAFK-Dnp-OH as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against angiotensin-converting enzyme (ACE).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against EndopeptidaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Compound was tested for inhibition of rat kidney neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Concentration for 50% inhibition of activity of rat kidney enkephalinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Tested for binding affinity against ThermolysinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Tested for inhibition against neutral endopeptidase (NEP)More data for this Ligand-Target Pair