BDBM50024284 CHEMBL3334979

SMILES COc1ccc(cc1OC)-c1cnc2scc(NC(=O)C3CCCCC3)c2c1

InChI Key InChIKey=HGVYGHNZFIZVJT-UHFFFAOYSA-N

Data  22 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50024284   

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataKd:  9nMAssay Description:Binding affinity to DRAK2 (unknown origin) ATP siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDeath-associated protein kinase 3(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of human DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of DRAK1 (unknown origin) using 33P-ATP after 30 mins by Trilux scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  860nMAssay Description:Inhibition of DRAK2 (unknown origin) using 33P-ATP after 30 mins by Trilux scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  560nMAssay Description:Inhibition of DRAK1 (unknown origin) using 1 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  630nMAssay Description:Inhibition of DRAK1 (unknown origin) using 5 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  710nMAssay Description:Inhibition of DRAK1 (unknown origin) using 10 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  940nMAssay Description:Inhibition of DRAK1 (unknown origin) using 25 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of DRAK1 (unknown origin) using 50 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of DRAK1 (unknown origin) using 100 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of DRAK1 (unknown origin) using 250 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  5.91E+3nMAssay Description:Inhibition of DRAK1 (unknown origin) using 500 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  370nMAssay Description:Inhibition of DRAK2 (unknown origin) using 1 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  510nMAssay Description:Inhibition of DRAK2 (unknown origin) using 5 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  530nMAssay Description:Inhibition of DRAK2 (unknown origin) using 10 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  650nMAssay Description:Inhibition of DRAK2 (unknown origin) using 25 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  720nMAssay Description:Inhibition of DRAK2 (unknown origin) using 50 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  990nMAssay Description:Inhibition of DRAK2 (unknown origin) using 100 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of DRAK2 (unknown origin) using 250 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  2.22E+3nMAssay Description:Inhibition of DRAK2 (unknown origin) using 500 uM ATP by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17B(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of recombinant GST-tagged DRAK2 (unknown origin) autophosphorylation after 2 hrs by ADP-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of human DRAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDeath-associated protein kinase 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human DAPK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase 17A(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50024284(CHEMBL3334979)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to DRAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed