BDBM50024471 4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoic acid::CHEMBL22290

SMILES Nc1nc2CCC(CN(CC#C)c3ccc(cc3)C(O)=O)Cc2c(=O)[nH]1

InChI Key InChIKey=NLUYCHXZUFSXEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024471   

TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024471(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)
Affinity DataIC50:  1.90E+5nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024471(4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazolin...)
Affinity DataIC50:  6.10E+5nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed