BDBM50025016 CHEMBL3337849

SMILES CN(C)c1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1

InChI Key InChIKey=SMLSSWCSSCTQSJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50025016   

TargetCasein kinase I isoform delta(Rat)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025016(CHEMBL3337849)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat CK1delta by radiometric protein kinase filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Rat)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025016(CHEMBL3337849)
Affinity DataIC50: 180nMAssay Description:Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Rat)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025016(CHEMBL3337849)
Affinity DataIC50: 210nMAssay Description:Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
Ulm University Hospital

Curated by ChEMBL
LigandPNGBDBM50025016(CHEMBL3337849)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant CK1epsilon expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed