BDBM50025040 CHEMBL3355098

SMILES CC[C@@H]7C[N+]9(Cc1ccc([N+](=O)[O-])cc1)CC[C@@]8%11c2ccccc2N%10/C=C\%12C5CC3[C@@]%13(CC[N+]3(Cc4ccc([N+](=O)[O-])cc4)C[C@H]5CC)c6ccccc6N(/C=C([C@H]7C[C@@H]89)\[C@H]%10%11)[C@@H]%12%13

InChI Key InChIKey=INEXDFNNPUNNJK-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50025040   

TargetMuscarinic acetylcholine receptor M2(Pig)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataEC50:  49nMAssay Description:Displacement of [3H]NMS from pig muscarinic M2 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Pig)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataEC50:  49nMAssay Description:Displacement of [3H]NMS from pig muscarinic M2 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in GH3 cells by Ca2+/Fluo-4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataIC50: 2.14E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in GH3 cells by Ca2+/Fluo-4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed