BDBM50025078 1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-ethylamine::CHEMBL31081

SMILES CC(N)Cc1cc2CCNc2cc1C

InChI Key InChIKey=KMDNCNZLZNDTAF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50025078   

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025078(1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibition of NE uptake at NE uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025078(1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vivo inhibition of DA uptake at dopamine uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025078(1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...)
Affinity DataIC50: 1.30E+4nMAssay Description:Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025078(1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...)
Affinity DataIC50: 1.60E+4nMAssay Description:Compound was tested in vitro for inhibition of Serotonin transporter uptake at serotonin uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025078(1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...)
Affinity DataIC50: 1.70E+5nMAssay Description:Compound was tested in vitro for inhibition of MAO by using [14C]phenylethylamine as substrate in rat brain mitochondrial preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed