BDBM50025148 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-3,5-dichloro-benzoylamino}-pentanedioic acid::CHEMBL357672

SMILES C#CCN(Cc1ccc2nc(N)[nH]c(=O)c2c1)c1c(Cl)cc(C(=O)NC(CCC(=O)O)C(=O)O)cc1Cl

InChI Key InChIKey=BJWCOCPYUFMOQD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025148   

TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025148BDBM50025148(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of L1210 thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025148BDBM50025148(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 3.00E+3nMAssay Description:The compound was evaluated in vitro for inhibition of purified L1210 dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025148BDBM50025148(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of L1210 thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed