BDBM50026645 CHEMBL3331465

SMILES CC(C)c1c(COC(=O)Cc2ccccc2Nc2c(Cl)cccc2Cl)n(C)n(-c2ccccc2)c1=O

InChI Key InChIKey=TYDJUENTMIDQHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50026645   

TargetProstaglandin G/H synthase 1(Sheep)
Minia University

Curated by ChEMBL
LigandPNGBDBM50026645(CHEMBL3331465)
Affinity DataIC50: 250nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Minia University

Curated by ChEMBL
LigandPNGBDBM50026645(CHEMBL3331465)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver estera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50026645(CHEMBL3331465)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed