BDBM50027046 2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-3-methyl-butyrylamino]-succinic acid::CHEMBL134414

SMILES CC(C)CC(N)C(O)C(=O)NC(C(C)C)C(=O)NC(CC(O)=O)C(O)=O

InChI Key InChIKey=DEDGWGRBYGQEIJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50027046   

TargetAminopeptidase N(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50027046(2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-3-...)
Affinity DataKi:  900nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50027046(2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-3-...)
Affinity DataKi:  940nMAssay Description:Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) and the inhibition constant was determined after preincubating the enzyme and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50027046(2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-3-...)
Affinity DataKi:  1.24E+3nMAssay Description:Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50027046(2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-3-...)
Affinity DataKi:  4.00E+4nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed