BDBM50027184 CHEMBL180700

SMILES O=C1COc2ccc(OCCNCCCOc3cccc4[nH]ccc34)cc2N1

InChI Key InChIKey=YORRFXCSZXGULE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50027184   

Target5-hydroxytryptamine receptor 1A(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50027184(CHEMBL180700)
Affinity DataKi:  1.60nMAssay Description:Negative logarithm causing 50% receptor occupancy against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50027184(CHEMBL180700)
Affinity DataKi:  1.60nMAssay Description:Mean negative logarithim of binding affinity was measured for the human 5-hydroxytryptamine 1A receptor; n>/=3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50027184(CHEMBL180700)
Affinity DataKi:  79nMAssay Description:Mean negative logarithim of binding affinity was measured for the rat serotonin transporter; n>/=3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50027184(CHEMBL180700)
Affinity DataKi:  79nMAssay Description:Negative logarithm causing 50% receptor occupancy against serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50027184(CHEMBL180700)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity for human beta-2 adrenergic receptor by displacing [125I]iodocyanopindolol expressed in hamster CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50027184(CHEMBL180700)
Affinity DataKi:  1.00E+3nMAssay Description:Negative logarithm causing 50% receptor occupancy against beta-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed