BDBM50027923 CHEMBL1161227::Phosphoric acid mono-[3-hydroxy-5-(4-hydroxyamino-2-oxo-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl] ester

SMILES ONc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2)c(=O)n1

InChI Key InChIKey=YKOWBJJOJNGCAD-UHFFFAOYSA-N

Data  1 KI  1 Kd

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027923   

TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027923(CHEMBL1161227 | Phosphoric acid mono-[3-hydroxy-5-...)
Affinity DataKi:  8.00E+3nMAssay Description:The apparent associaton constant (Ki) of the compound with dTMP synthetase enzyme from chick embryo in the absence of CH2-H4 folate was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50027923(CHEMBL1161227 | Phosphoric acid mono-[3-hydroxy-5-...)
Affinity DataKd:  1.00E+3nMAssay Description:Compound was evaluated for average apparent binding constant (Kd ) using Scatchard analysis to dTMP synthetase enzyme from chick embryoMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMedPDB3D3D Structure (crystal)