BDBM50028217 CHEMBL3354037

SMILES OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccc3cccc4ccc1c2c34

InChI Key InChIKey=IMYBJLKJUZUZCD-KBJUPQRZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028217   

TargetCeramide glucosyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028217(CHEMBL3354037)
Affinity DataIC50:  3nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028217(CHEMBL3354037)
Affinity DataIC50:  1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal acid glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028217(CHEMBL3354037)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed