BDBM50028866 CHEMBL297271::N-[(1S,2R)-2-(4-Hydroxy-phenyl)-indan-1-yl]-2,2-diphenyl-acetamide

SMILES Oc1ccc(cc1)[C@H]1Cc2ccccc2[C@H]1NC(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=ZPORBGGQIAIHNC-IXCJQBJRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028866   

TargetSterol O-acyltransferase 1(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50028866(CHEMBL297271 | N-[(1S,2R)-2-(4-Hydroxy-phenyl)-ind...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity of the compound against Acyl coenzyme A:cholesterol acyltransferase 1 from rat hepatic microsomes at 10 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50028866(CHEMBL297271 | N-[(1S,2R)-2-(4-Hydroxy-phenyl)-ind...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50028866(CHEMBL297271 | N-[(1S,2R)-2-(4-Hydroxy-phenyl)-ind...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against acyl-coenzyme A:cholesterol acyltransferase 1 from rat hepatic microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed