BDBM50029389 1-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-3,3-dimethyl-piperazine::CHEMBL136648

SMILES CC1(C)CN(CCN1)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=DLAZTOJTTMSVCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029389   

TargetD(1A) dopamine receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029389(1-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029389(1-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50:  5.20nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50029389(1-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...)
Affinity DataIC50:  7.5nMAssay Description:Binding affinity for 5-hydroxytryptamine 2A receptor, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed