BDBM50029505 5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1S)-butyl]-1-[2-methylamino-3-phenyl-(2S)-propanoyl]-(5S)-dihydro-1H-5-pyrrolecarboxamide::CHEMBL336471

SMILES CN[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@](C)(CCCNC(N)=N)C=O

InChI Key InChIKey=CVOKUEIRLXMZAG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029505   

TargetProthrombin(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029505(5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029505(5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1...)
Affinity DataIC50: 2.40E+5nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029505(5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1...)
Affinity DataIC50: 8.50E+5nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029505(5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1...)
Affinity DataIC50: 1.80E+6nMAssay Description:In vitro Enzyme Inhibitory activity measured against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029505(5N-[4-amino(imino)methylamino-1-formyl-1-methyl-(1...)
Affinity DataIC50: 3.00E+7nMAssay Description:In vitro Enzyme Inhibitory activity against t-PA(Tissue plasminogen activator).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed