BDBM50029747 (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid::(alpha-MSH)Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2::Ac-S-Y-S-M-E-H-F-R-W-G-K-P-V-NH2::Ac-Ser-Tyr-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2::Ac-Ser-Tyr-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2::Ac-Ser-Tyr-Ser-Met-Glu-His--Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2::Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2(alpha-MSH)::Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2(alpha-Melanotropin, MSH)::Ac-Ser-Tyr-Ser-Met-Glu-His6-Phe7-Arg8-Trp9-Gly-Lys-Pro-Val-NH2::Ac-ser-tyr-ser-met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2::CHEMBL214332::alpha-MSH (Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2)::alpha-MSH; Ac-Ser-Tyr-Ser-Met-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pro-Val-NH2
SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
InChI Key InChIKey=WHNFPRLDDSXQCL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 156 hits for monomerid = 50029747
Affinity DataEC50: 0.0400nMAssay Description:Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0910nMAssay Description:Effective concentration required for the biological activity against human Melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0910nMAssay Description:Evaluated for agonist activity against human Melanocortin 1 receptor using hMC1-R assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0910nMAssay Description:Evaluated for agonist activity at cloned mammalian human MSH1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Evaluated for agonist at cloned mammalian Melanocortin 1 receptor in frog (Rana pipiens) skin assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Decrease in frog skin reflectivity (metabotropic activity).More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Effective concentration for the effect of Melanocortin 1 receptor in the frog skin.More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Effective concentration required for maximum agonist response at melanocortin 1 receptor from frog skin.More data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at mouse melanocortin 1 receptor expressed in HEK293 cells by AlphaScreen cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.150nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Effective concentration required for the biological activity against human Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Evaluated for agonist activity at cloned mammalian Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Agonist activity at mouse MC5 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.220nMAssay Description:Agonist activity at mouse melanocortin receptor 5 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.230nMAssay Description:Functional activity at the mouse melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.280nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells by beta-galactosidase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.320nMAssay Description:Effective concentration for mouse Melanocortin-5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:In vitro agonist potency for Mouse Melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonistic activity evaluated at melanocortin 5 receptor (MC5R) of mouse HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at mouse MC3 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.410nMAssay Description:Functional activity at the mouse melanocortin 5 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.440nMAssay Description:Agonist activity towards mouse Melanocortin-5 receptor (mMC5R)More data for this Ligand-Target Pair
Affinity DataEC50: 0.440nMAssay Description:Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.440nMAssay Description:In vitro activation of mouse recombinant Melanocortin-5 receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 0.440nMAssay Description:Effective concentration against mouse Melanocortin 5 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at mouse melanocortin 3 receptor expressed in HEK293 cells by AlphaScreen cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Effective concentration for mouse Melanocortin-1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.510nMAssay Description:Agonist activity at mouse melanocortin 5 receptor expressed in HEK293 cells by AlphaScreen cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.520nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells by beta-galactosidase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.530nMAssay Description:In vitro agonist potency for Mouse Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.550nMAssay Description:In vitro activation of mouse recombinant Melanocortin-1 receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 0.550nMAssay Description:Agonist activity to the mouse Melanocortin-1 receptor (mMC1R)More data for this Ligand-Target Pair
Affinity DataEC50: 0.550nMAssay Description:Effective concentration against mouse Melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.550nMAssay Description:Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.570nMAssay Description:Effective concentration for mouse Melanocortin-3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.590nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Agonistic activity evaluated at melanocortin 1 receptor (MC1R) of mouse HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.650nMAssay Description:Agonist activity at wild type human melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assess...More data for this Ligand-Target Pair
Affinity DataEC50: 0.669nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.670nMAssay Description:Effective concentration required for the biological activity against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:In vitro agonist potency for Mouse Melanocortin 5 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 1 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataEC50: 0.730nMAssay Description:Functional activity at the mouse melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.760nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:In vitro activation of mouse recombinant Melanocortin-3 receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:Agonist activity to the mouse Melanocortin-3 receptor (mMC3R)More data for this Ligand-Target Pair