BDBM50029789 5-(3-Hydroxy-phenyl)-2-methyl-8-[1-naphthalen-2-yl-meth-(E)-ylidene]-2-aza-bicyclo[3.3.1]nonan-7-one::CHEMBL145780

SMILES CN1CCC2(CC1C(=Cc1ccc3ccccc3c1)C(=O)C2)c1cccc(O)c1

InChI Key InChIKey=ONTJNYPJIFDYJB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029789   

TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029789(5-(3-Hydroxy-phenyl)-2-methyl-8-[1-naphthalen-2-yl...)
Affinity DataKi:  2.20nMAssay Description:Ability to inhibit [3H]DAMGO binding to rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029789(5-(3-Hydroxy-phenyl)-2-methyl-8-[1-naphthalen-2-yl...)
Affinity DataKi:  16.6nMAssay Description:Ability to inhibit [3H](+)-pentazocine binding to guinea pig brain Sigma receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029789(5-(3-Hydroxy-phenyl)-2-methyl-8-[1-naphthalen-2-yl...)
Affinity DataKi:  142nMAssay Description:Ability to inhibit [3H]DADLE binding to rat brain delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029789(5-(3-Hydroxy-phenyl)-2-methyl-8-[1-naphthalen-2-yl...)
Affinity DataKi: >500nMAssay Description:Ability to inhibit [3H]U-69593 binding to guinea pig Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed