BDBM50030757 CHEMBL3342196
SMILES CN1CCN(CCCNc2ncnc3n(ncc23)-c2ccc(OCCCc3sc(nc3C(O)=O)N3CCc4cccc(C(=O)Nc5nc6ccccc6s5)c4C3)cc2)CC1
InChI Key InChIKey=UYKNWWODISPUHU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50030757
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of BCL-2 (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inhibition of BCL-XL (unknown origin) expressed in mcl-1 deficient MEF assessed as induction of cell killing incubated for 48 hrs in presence of 10% ...More data for this Ligand-Target Pair