BDBM50031136 1-{4-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-4-methyl-phenylsulfanyl]-phenyl}-ethanone oxime::CHEMBL125792

SMILES COC1(CCOCC1)c1cc(Sc2ccc(cc2)C(C)N=O)cc(F)c1C

InChI Key InChIKey=OSBSOOYRLTVASU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031136   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031136(1-{4-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of LT biosynthesis in vitro using A-23187-stimulated human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed