BDBM50031141 1-{4-[4-(2,2,4-Trimethyl-[1,3]dioxolan-4-yl)-thiophen-2-ylsulfanyl]-phenyl}-ethanone oxime::CHEMBL128464

SMILES CC(N=O)c1ccc(Sc2cc(cs2)C2(C)COC(C)(C)O2)cc1

InChI Key InChIKey=KADXHSAARFZZMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031141   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031141(1-{4-[4-(2,2,4-Trimethyl-[1,3]dioxolan-4-yl)-thiop...)
Affinity DataIC50: 40nMAssay Description:Inhibition of LT biosynthesis in vitro using A-23187-stimulated human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed