BDBM50031142 CHEMBL129448::[1-{4-[4-((S)-2,2,4-Trimethyl-[1,3]dioxolan-4-yl)-thiophene-2-sulfonyl]-phenyl}-eth-(E)-ylideneaminooxy]-acetonitrile

SMILES C\C(=N/OCC#N)c1ccc(cc1)S(=O)(=O)c1cc(cs1)[C@@]1(C)COC(C)(C)O1

InChI Key InChIKey=CCHOKILJJHRUDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031142   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031142([1-{4-[4-((S)-2,2,4-Trimethyl-[1,3]dioxolan-4-yl)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of LT biosynthesis in vitro using A-23187-stimulated human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed