BDBM50031151 1-Methyl-7-[4-(2,2,4-trimethyl-[1,3]dioxolan-4-yl)-thiophen-2-ylsulfanyl]-3,4-dihydro-1H-quinolin-2-one::CHEMBL129098

SMILES CN1C(=O)CCc2ccc(Sc3cc(cs3)C3(C)COC(C)(C)O3)cc12

InChI Key InChIKey=HEFRGZXCFVAFAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031151   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031151(1-Methyl-7-[4-(2,2,4-trimethyl-[1,3]dioxolan-4-yl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of LT biosynthesis in vitro using A-23187-stimulated human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed