BDBM50031339 CHEMBL3358096

SMILES CCOc1cc(ccc1OCCOCCOCCOC)-c1nc([C@@H](C)Sc2nc(N)cc(N)n2)c(C)s1

InChI Key InChIKey=LCIRQJMVFQSFQG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031339   

TargetDeoxycytidine kinase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031339(CHEMBL3358096)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDeoxycytidine kinase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031339(CHEMBL3358096)
Affinity DataKi:  14nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetDeoxycytidine kinase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031339(CHEMBL3358096)
Affinity DataIC50: 32nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed