BDBM50031373 CHEMBL3358509

SMILES O=C(NCCCCN1CCN(CC1)c1ccccc1)c1ccc2ncccc2c1

InChI Key InChIKey=OURPZJJZFFKVJH-UHFFFAOYSA-N

Data  7 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50031373   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataKi:  66nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataKi:  99nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataKi:  110nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataKi:  150nMAssay Description:Binding affinity to alpha2 adrenoreceptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataIC50:  258nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO-K1 cells assessed as reduction in dopamine-induced response by [35S]GTPgammaS bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human 5HT1A receptor (unknown origin) expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataIC50:  2.60E+3nMAssay Description:Antagonist activity at 5HT2A receptor in rat aortic rings assessed as reduction in 5-HT-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50031373(CHEMBL3358509)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG by whole cell based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed