BDBM50031537 2-Butyl-3-(N'-propylureidylsulfonyl-biphenyl-4-ylmethyl)-5-methylsulfanyl-3H-imidazole-4-carboxylic acid(HR720)::2-butyl-1-[[2'-[[[(propylamino)carbonyl]amino]sulfonyl]-(1,1'-biphenyl)-4yl]methyl]-4-(methylthio)-1H-imidazole-5-carboxylic acid::5-carboxyl imidazolyl biphenyl sulfonylurea derivative::CHEMBL76525

SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCCC

InChI Key InChIKey=DKCCTYVLJMSFOG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031537   

TargetType-1 angiotensin II receptor A/B(Rat)
Hoechst Roussel Pgu Cardiovascular Agents

Curated by ChEMBL
LigandPNGBDBM50031537(5-carboxyl imidazolyl biphenyl sulfonylurea deriva...)
Affinity DataIC50: 0.300nMAssay Description:Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A/B(Rat)
Hoechst Roussel Pgu Cardiovascular Agents

Curated by ChEMBL
LigandPNGBDBM50031537(5-carboxyl imidazolyl biphenyl sulfonylurea deriva...)
Affinity DataIC50: 0.5nMAssay Description:In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2018
Entry Details

TargetType-2 angiotensin II receptor(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031537(5-carboxyl imidazolyl biphenyl sulfonylurea deriva...)
Affinity DataIC50: 920nMAssay Description:Inhibitory activity was evaluated against Angiotensin II receptor, type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
LigandPNGBDBM50031537(5-carboxyl imidazolyl biphenyl sulfonylurea deriva...)
Affinity DataIC50: 920nMAssay Description:In vitro displacement of [125I]angiotensin II from angiotensin 2 receptor on rabbit uterus membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2018
Entry Details