BDBM500316 US11021475, Example 183

SMILES CNC(=O)c1nnc(Nc2cc(C)nc(C)n2)cc1Nc1cccc(-c2nc(C)n(C)n2)c1OC

InChI Key InChIKey=JCJKLDMUTGQQBS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 500316   

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM500316(US11021475, Example 183)
Affinity DataEC50:  5.72nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent