BDBM50031644 1-(4-Benzyloxy-phenyl)-3-dimethylamino-2-(3,4-dimethyl-phenylsulfanylmethyl)-propan-1-one; hydrochloride::CHEMBL538507

SMILES CN(C)CC(CSc1ccc(C)c(C)c1)C(=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=JAWVVQKVYZUJTE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031644   

TargetEpidermal growth factor receptor(Human)
Ciba

Curated by ChEMBL
LigandPNGBDBM50031644(1-(4-Benzyloxy-phenyl)-3-dimethylamino-2-(3,4-dime...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibition of the Epidermal growth factor receptor activity in A431 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ciba

Curated by ChEMBL
LigandPNGBDBM50031644(1-(4-Benzyloxy-phenyl)-3-dimethylamino-2-(3,4-dime...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of the v-abl tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50031644(1-(4-Benzyloxy-phenyl)-3-dimethylamino-2-(3,4-dime...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of the c-src tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed